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Orthobiologics

SynerG™ Orthobiologics

Precision Biologic Care, Measured by Outcomes
Biologics aren’t one-size-fits-all. At SIGMA, SynerG standardizes how we prepare, deliver, and measure orthobiologics—using ultrasound guidance, strict processing protocols, and your PROs—so you know what you’re getting, why you’re getting it, and how we’ll track your progress.
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What are Orthobiologics?

Orthobiologics are treatments prepared from your own blood, bone marrow, or adipose tissue—or from purified proteins—that may help reduce inflammation, support tissue healing, and relieve pain. At SIGMA, our SynerG approach applies Six Sigma discipline to each step—selection, preparation, image-guided delivery, and outcomes tracking—to improve consistency and decision-making over time.

Who’s a Candidate?

  • Tendonitis and low-grade tendon tears
  • Cartilage injury and focal chondral defects
  • Joint pain and mild–moderate knee osteoarthritis

Treatments

ACP (Autologous Conditioned Plasma):

Concentrated plasma from your own blood; considered for tendon-related pain and select joint issues.

PRP (Platelet-Rich Plasma):

Platelet concentrate prepared under standardized spin protocols; ultrasound-guided delivery for precision.

A2M (Alpha-2-Macroglobulin):

A naturally occurring protease inhibitor; considered when enzyme-driven inflammation is suspected.

Adipose-Derived Cell Preparations:

Carefully harvested and processed adipose tissue preparations; discuss candidacy and regulatory considerations.

BMAC (Bone Marrow–Derived Cell Preparations):

Aspirated bone marrow concentrate; used selectively for cartilage or tendon pathology after shared decision-making.

Process Steps

Step 01
Assessment & Imaging

Confirm diagnosis; consider ultrasound as part of targeting plan.

Step 02
Standardized Preparation

Defined kits/spin times, documented lot numbers.

Step 03
Ultrasound-Guided Delivery

Real-time targeting to the intended tissue.

Step 04
Recovery Toolkit:

Link patients to Cryotherapy, TENS, Nutrition Optimization pages to reduce pain and support healing. Dr Frank McCormick

Step 05
Outcomes Tracking

Enroll in Patient-Reported Outcomes with benchmarks and follow-ups. Dr Frank McCormick

Compliance & safety microcopy (patient-friendly):
Biologic options vary in regulatory status and insurance coverage. We’ll review benefits, risks, costs, and alternatives so you can decide confidently.

FREQUENTLY ASKED QUESTIONS

Does insurance cover these treatments?
Coverage depends on the product and indication; we’ll outline costs up front.
Most plans start with one treatment and reassess at 6–12 weeks using outcomes and exam.
Most patients return to desk work within 24–48 hours; sports return is individualized.
We perform ultrasound-guided injections for precise placement.
We revisit the diagnosis, rehab plan, and other options—including surgical pathways when appropriate.

CTA – Am I a Candidate?

SIGMA Intake System

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